Create a scientific figure about: DNA damage sensing and checkpoint activation by ATM-ATR.
Visual style: Isometric Technical.
Requirements:
- publication-ready scientific quality
- clear labels and directional arrows where appropriate
- avoid cartoon style, avoid meme style, avoid stock-photo look
- avoid neon glow and over-sharpened CGI look unless explicitly requested
- composition optimized for research papers and academic slides
- category context: mechanisms-pathways
- isometric perspective with precise component geometry
- engineering-style callouts and measured spacing
- moderate blue-gray palette with restrained accent colors
