Create a graphical abstract for a lipid nanoparticle mRNA delivery paper: ionizable lipid/DSPC/cholesterol/PEG-lipid self-assembly around mRNA cargo using microfluidic mixing, LNP characterization (DLS size ~80nm, PDI, encapsulation efficiency), intramuscular injection, cellular uptake via macropinocytosis, endosomal escape mediated by ionizable lipid protonation at low pH, mRNA release into cytoplasm, ribosomal translation of encoded antigen, MHC-I/II presentation, B cell antibody response and CD8+ T cell activation. Circular layout.
