Create a graphical abstract for a CAR-T cell therapy paper: (1) patient leukapheresis and T cell isolation, (2) CAR construct design with anti-CD19 scFv, CD28/4-1BB costimulatory domain, and CD3ζ signaling domain connected by lentiviral transduction, (3) ex vivo T cell expansion in bioreactor, (4) lymphodepletion conditioning, (5) CAR-T cell infusion and in vivo expansion, (6) CD19+ B-cell lymphoma targeted killing with cytokine release. Show tumor regression endpoint with survival curve. Journal-quality single-panel summary figure.
